Semisynthesis of Bioactive Compounds and their Biological Activities 1st Edition By Sasadhar Majhi, Sivakumar Manickam
Semisynthesis of Bioactive Compounds and Their Biological Activities (1st Edition), authored by Sasadhar Majhi and Sivakumar Manickam, was published by Elsevier in late 2023 (copyright 2024). The book provides a comprehensive exploration of how natural compounds can be chemically modified to enhance their biological properties and therapeutic potential. Key Publication Details
- Release Date: December 8, 2023
- ISBN-13: 978-0443152696
- Print Length: Approximately 500 pages
- Language: English
Book Overview and SectionsThe text serves as a resource for researchers in drug development, focusing on the natural distribution of parent compounds and the applications of their semisynthetic derivatives in fields such as medicine, drug delivery, and food production. It specifically covers:
- Antibiotics: Discusses current resistance mechanisms, chemical derivatization (e.g., glycopeptides, lipopeptides), and clinical applications.
- Plant-Derived Compounds: Detailed sections on the semisynthesis of alkaloids, flavones, lignans, and anthocyanins.
- Sustainable Chemistry: Highlights green synthesis tools, including microwave technology, sonochemistry, and eco-friendly catalysts to perform reactions under greener conditions.
- Novel Modifications: Covers the insertion of oxygen atoms under metal-free conditions and regulatory aspects of novel derivatives as nutraceuticals.
About the Authors
- Sasadhar Majhi: A researcher and coordinator in the Department of Chemistry at Triveni Devi Bhalotia College, West Bengal, India. His expertise includes the isolation and structural determination of natural products and green chemistry.
- Sivakumar Manickam: A chemical engineer and professor at the University of Technology Brunei. He has over 25 years of experience in process engineering, nanomaterials, and cavitation reactors.